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Replication stress conferred by POT1 dysfunction promotes telomere relocalization to the nuclear pore.
Pinzaru AM, Kareh M, Lamm N, Lazzerini-Denchi E, Cesare AJ, Sfeir A
Genes Dev. 2020 Dec 1;34(23-24):1619-1636. doi: 10.1101/gad.337287.120. Epub 2020 Oct 29.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
166406pWZL N-Myc-hPOT1_IRES_hygroexpress hPOT1 in mammalian cells
166407pWZL N-Myc-hPOT1_K90E-IRES_hygroExpress hPOT1 K90E in mammalian cells
166408pWZL N-Myc-hPOT1_deltaOBexpress hPOT1 ΔOB in mammalian cells
166409pLPC-N-Myc-Flag-BirA-hPOT1express BirA-hPOT1 in mammalian cells
166410pLPC-N-Myc-Flag-BirA-hPOT1-DeltaOBexpress BirA-hPOT1 ΔOB in mammalian cells
166411pHAGE2-EF1a-MCS-hPOT1_IRES-blastexpress hPOT1 in mammalian cells
166412pHAGE2-EF1a-MCS-hPOT1_K90E_IRES-blastexpress hPOT1 K90E in mammalian cells
166413pHAGE2-EF1a-MCS-dOB-hPOT1_IRES-blastexpress hPOT1 ΔOB in mammalian cells

Antibodies from Article