Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science. 2021 Jun 24. pii: science.abi6226. doi: 10.1126/science.abi6226. PubMed Article
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science. 2021 Jun 24. pii: science.abi6226. doi: 10.1126/science.abi6226. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 171743 | pαH-S-GSAS-D614G-deltaFV | Mammalian expression of SARS-CoV-2 Spike protein mink variant (S-GSAS-D614G-deltaFV variant) |
| 171744 | pαH-S-GSAS-deltaH69/V70 | Mammalian expression of SARS-CoV-2 Spike protein S-GSAS-D614G-deltaH69/V70 variant |
| 171745 | pαH-S-GSAS-D614G-Y453F | Mammalian expression of SARS-CoV-2 Spike protein S-GSAS-D614G-Y453F variant |
| 171746 | pαH-S-GSAS-D614G-I692V | Mammalian expression of SARS-CoV-2 Spike protein S-GSAS-D614G-I692V variant |
| 171747 | pαH-S-GSAS-B.1.1.7 | Mammalian expression of SARS-CoV-2 Spike protein S-GSAS-B.1.1.7 variant (UK) |
| 171748 | pαH-S-GSAS-D614G-N501Y | Mammalian expression of SARS-CoV-2 Spike protein S-GSAS-D614G-N501Y variant |
| 171749 | pαH-S-GSAS-B.1.351 | Mammalian expression of SARS-CoV-2 Spike protein S-GSAS-D614G-B.1.351 variant (South African) |
| 171750 | pαH-S-GSAS-D614G-K417N-E484K-N501Y | Mammalian expression of SARS-CoV-2 Spike protein S-GSAS-D614G-K417N-E484K-N501Y |
| 171751 | pαH-S-GSAS-D614G-E484K | Mammalian expression of SARS-CoV-2 Spike protein S-GSAS-D614G-E484K variant |
| 171752 | pαH-S-GSAS-D614G-K417N | Mammalian expression of SARS-CoV-2 Spike protein S-GSAS-D614G-K417N variant |
| 173786 | pαH-S-GSAS-B.1.351.v2 | Mammalian expression of SARS-CoV-2 Spike protein South African variant version 2 |
| 173787 | pαH-S-GSAS-B.1.351.v3 | Mammalian expression of SARS-CoV-2 Spike protein South African variant version 3 |
| 173788 | pαH-S-GSAS-B.1.351.v4 | Mammalian expression of SARS-CoV-2 Spike protein South African variant version 4 |
| 173789 | pαH-S-GSAS-P1-like | Mammalian expression of SARS-CoV-2 Spike protein P-1-like variant (K417N) |
| 173790 | pαH-S-GSAS-B.1.351.v5 | Mammalian expression of SARS-CoV-2 Spike protein South African variant version 5 |
| 173791 | pαH-S-GSAS-B.1.351.v6 | Mammalian expression of SARS-CoV-2 Spike protein South African variant version 6 |