Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export.
Martin S, Smolders S, Van den Haute C, Heeman B, van Veen S, Crosiers D, Beletchi I, Verstraeten A, Gossye H, Gelders G, Pals P, Hamouda NN, Engelborghs S, Martin JJ, Eggermont J, De Deyn PP, Cras P, Baekelandt V, Vangheluwe P, Van Broeckhoven C
Acta Neuropathol. 2020 Jun;139(6):1001-1024. doi: 10.1007/s00401-020-02145-7. Epub 2020 Mar 14. PubMed Article
Martin S, Smolders S, Van den Haute C, Heeman B, van Veen S, Crosiers D, Beletchi I, Verstraeten A, Gossye H, Gelders G, Pals P, Hamouda NN, Engelborghs S, Martin JJ, Eggermont J, De Deyn PP, Cras P, Baekelandt V, Vangheluwe P, Van Broeckhoven C
Acta Neuropathol. 2020 Jun;139(6):1001-1024. doi: 10.1007/s00401-020-02145-7. Epub 2020 Mar 14. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 171770 | pLenti HsATP10B WT | transfer plasmid for lentiviral vector production expressing Hs ATP10B WT |
| 171789 | pLenti TMEM30A | transfer plasmid for lentiviral vector production expressing TMEM30A |
| 171790 | miR2 HsATP10B | transfer plasmid for lentiviral vector production with miR for Hs ATP10B |
| 171791 | miR5 MmATP10B | transfer plasmid for lentiviral vector production with miR for Mm ATP10B |
| 171823 | pLenti HsATP10B D433N | transfer plasmid for lentiviral vector production expressing Hs ATP10B D433N |
| 171824 | miR3 HsATP10B | transfer plasmid for lentiviral vector production with miR for Hs ATP10B |
| 171825 | miR7 MmATP10B | transfer plasmid for lentiviral vector production with miR for Mm ATP10B |