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Wbp2nl has a developmental role in establishing neural and non-neural ectodermal fates.
Marchak A, Grant PA, Neilson KM, Datta Majumdar H, Yaklichkin S, Johnson D, Moody SA
Dev Biol. 2017 Sep 1;429(1):213-224. doi: 10.1016/j.ydbio.2017.06.025. Epub 2017 Jun 27.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
172463pCS2+-wbp2nlexpresses wild-type protein when injected into embryos
172464pCS2+-wbp2nlT45Aexpresses protein with one aa substitution to affect potential phosphorylation
172466pCS2+-wbp2nlY55Fexpresses protein with one aa substitution to affect potential phosphorylation in ITSM domain
172467pCS2+5'MT-wbp2nlexpresses myc-tagged version of wild-type protein
172468pCS2+-wbp2nlY282Fexpresses protein with one aa substitution to affect potential phosphorylation in WW-interaction domain
174507pCS2+-wbp2nlF127Pexpresses protein with one aa substitution to disrupt the alpha-helix near the PH-G domain

Antibodies from Article