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PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS.
Nieuwenhuis B, Barber AC, Evans RS, Pearson CS, Fuchs J, MacQueen AR, van Erp S, Haenzi B, Hulshof LA, Osborne A, Conceicao R, Khatib TZ, Deshpande SS, Cave J, Ffrench-Constant C, Smith PD, Okkenhaug K, Eickholt BJ, Martin KR, Fawcett JW, Eva R
EMBO Mol Med. 2020 Aug 7;12(8):e11674. doi: 10.15252/emmm.201911674. Epub 2020 Jun 17.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
203797pLV-SFFV-PIK3CA-WPRE-UbC-EmeraldLentiviral vector expressing human phosphoinositide 3-kinase catalytic subunit alpha (PIK3CA) under the spleen focus-forming virus (SFFV) promoter and Emerald under the Ubiquitin C (UbC) promoter
203798pLV-SFFV-PIK3CA H1047R-WPRE-UbC-EmeraldLentiviral vector expressing human PIK3CA H1047R under the spleen focus-forming virus (SFFV) promoter and Emerald under the Ubiquitin C (UbC) promoter

Antibodies from Article