A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer.
Cai H, Chew SK, Li C, Tsai MK, Andrejka L, Murray CW, Hughes NW, Shuldiner EG, Ashkin EL, Tang R, Hung KL, Chen LC, Lee SYC, Yousefi M, Lin WY, Kunder CA, Cong L, McFarland CD, Petrov DA, Swanton C, Winslow MM
Cancer Discov. 2021 Feb 19. pii: 2159-8290.CD-20-1325. doi: 10.1158/2159-8290.CD-20-1325. PubMed Article
Cai H, Chew SK, Li C, Tsai MK, Andrejka L, Murray CW, Hughes NW, Shuldiner EG, Ashkin EL, Tang R, Hung KL, Chen LC, Lee SYC, Yousefi M, Lin WY, Kunder CA, Cong L, McFarland CD, Petrov DA, Swanton C, Winslow MM
Cancer Discov. 2021 Feb 19. pii: 2159-8290.CD-20-1325. doi: 10.1158/2159-8290.CD-20-1325. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 173569 | Lenti-sgArhgap35#1/Cre | Expresses a Arhgap35-targeting gRNA and Cre-recombinase |
| 173570 | Lenti-sgArhgap35#2/Cre | Expresses a Arhgap35-targeting gRNA and Cre-recombinase |
| 173571 | Lenti-sgArid1a#1/Cre | Expresses a Arid1a-targeting gRNA and Cre-recombinase |
| 173572 | Lenti-sgArid1a#2/Cre | Expresses a Arid1a-targeting gRNA and Cre-recombinase |
| 173573 | Lenti-sgArid1b#1/Cre | Expresses a Arid1b-targeting gRNA and Cre-recombinase |
| 173574 | Lenti-sgArid1b#2/Cre | Expresses a Arid1b-targeting gRNA and Cre-recombinase |
| 173575 | Lenti-sgArid2#1/Cre | Expresses a Arid2-targeting gRNA and Cre-recombinase |
| 173576 | Lenti-sgArid2#2/Cre | Expresses a Arid2-targeting gRNA and Cre-recombinase |
| 173577 | Lenti-sgAtf7ip#1/Cre | Expresses a Atf7ip-targeting gRNA and Cre-recombinase |
| 173578 | Lenti-sgAtf7ip#2/Cre | Expresses a Atf7ip-targeting gRNA and Cre-recombinase |
| 173579 | Lenti-sgAtm#1/Cre | Expresses a Atm-targeting gRNA and Cre-recombinase |
| 173580 | Lenti-sgAtm#2/Cre | Expresses a Atm-targeting gRNA and Cre-recombinase |
| 173581 | Lenti-sgBap1#1/Cre | Expresses a Bap1-targeting gRNA and Cre-recombinase |
| 173582 | Lenti-sgBap1#2/Cre | Expresses a Bap1-targeting gRNA and Cre-recombinase |
| 173583 | Lenti-sgCdkn2c#1/Cre | Expresses a Cdkn2c-targeting gRNA and Cre-recombinase |
| 173584 | Lenti-sgCdkn2c#2/Cre | Expresses a Cdkn2c-targeting gRNA and Cre-recombinase |
| 173585 | Lenti-sgCic#1/Cre | Expresses a Cic-targeting gRNA and Cre-recombinase |
| 173587 | Lenti-sgDnmt3a#1/Cre | Expresses a Dnmt3a-targeting gRNA and Cre-recombinase |
| 173588 | Lenti-sgDnmt3a#2/Cre | Expresses a Dnmt3a-targeting gRNA and Cre-recombinase |
| 173589 | Lenti-sgDot1l#1/Cre | Expresses a Dot1l-targeting gRNA and Cre-recombinase |
| 173590 | Lenti-sgDot1l#2/Cre | Expresses a Dot1l-targeting gRNA and Cre-recombinase |
| 173591 | Lenti-sgEp300#1/Cre | Expresses a Ep300-targeting gRNA and Cre-recombinase |
| 173592 | Lenti-sgEp300#2/Cre | Expresses a Ep300-targeting gRNA and Cre-recombinase |
| 173593 | Lenti-sgErcc4#1/Cre | Expresses a Ercc4-targeting gRNA and Cre-recombinase |
| 173594 | Lenti-sgErcc4#2/Cre | Expresses a Ercc4-targeting gRNA and Cre-recombinase |
| 173595 | Lenti-sgGata3#1/Cre | Expresses a Gata3-targeting gRNA and Cre-recombinase |
| 173596 | Lenti-sgGata3#2/Cre | Expresses a Gata3-targeting gRNA and Cre-recombinase |
| 173597 | Lenti-sgKmt2d#1/Cre | Expresses a Kmt2d-targeting gRNA and Cre-recombinase |
| 173598 | Lenti-sgKmt2d#2/Cre | Expresses a Kmt2d-targeting gRNA and Cre-recombinase |
| 173599 | Lenti-sgLats1#1/Cre | Expresses a Lats1-targeting gRNA and Cre-recombinase |
| 173600 | Lenti-sgLats1#2/Cre | Expresses a Lats1-targeting gRNA and Cre-recombinase |
| 173602 | Lenti-sgMga#2/Cre | Expresses a Mga-targeting gRNA and Cre-recombinase |
| 173603 | Lenti-sgNcoa6#1/Cre | Expresses a Ncoa6-targeting gRNA and Cre-recombinase |
| 173604 | Lenti-sgNcoa6#2/Cre | Expresses a Ncoa6-targeting gRNA and Cre-recombinase |
| 173605 | Lenti-sgNcor1#1/Cre | Expresses a Ncor1-targeting gRNA and Cre-recombinase |
| 173606 | Lenti-sgNcor1#2/Cre | Expresses a Ncor1-targeting gRNA and Cre-recombinase |
| 173607 | Lenti-sgNf1#1/Cre | Expresses a Nf1-targeting gRNA and Cre-recombinase |
| 173608 | Lenti-sgNf1#2/Cre | Expresses a Nf1-targeting gRNA and Cre-recombinase |
| 173609 | Lenti-sgPole#1/Cre | Expresses a Pole-targeting gRNA and Cre-recombinase |
| 173610 | Lenti-sgPole#2/Cre | Expresses a Pole-targeting gRNA and Cre-recombinase |
| 173612 | Lenti-sgAtrx#1/Cre | Expresses a Atrx-targeting gRNA and Cre-recombinase |
| 173613 | Lenti-sgRnf43#1/Cre | Expresses a Rnf43-targeting gRNA and Cre-recombinase |
| 173614 | Lenti-sgRnf43#2/Cre | Expresses a Rnf43-targeting gRNA and Cre-recombinase |
| 173615 | Lenti-sgSetd2#2/Cre | Expresses a Setd2-targeting gRNA and Cre-recombinase |
| 173616 | Lenti-sgAtrx#2/Cre | Expresses a Atrx-targeting gRNA and Cre-recombinase |
| 173617 | Lenti-sgSmad4#1/Cre | Expresses a Smad4-targeting gRNA and Cre-recombinase |
| 173618 | Lenti-sgSmad4#2/Cre | Expresses a Smad4-targeting gRNA and Cre-recombinase |
| 173619 | Lenti-sgSmarca4#1/Cre | Expresses a Smarca4-targeting gRNA and Cre-recombinase |
| 173620 | Lenti-sgSmarca4#2/Cre | Expresses a Smarca4-targeting gRNA and Cre-recombinase |
| 173621 | Lenti-sgTp53#2/Cre | Expresses a Tp53-targeting gRNA and Cre-recombinase |
| 173622 | Lenti-sgTp53#3/Cre | Expresses a Tp53-targeting gRNA and Cre-recombinase |
| 173623 | Lenti-sgUbr5#1/Cre | Expresses a Ubr5-targeting gRNA and Cre-recombinase |
| 173624 | Lenti-sgUbr5#2/Cre | Expresses a Ubr5-targeting gRNA and Cre-recombinase |
| 173625 | Lenti-sgWrn#1/Cre | Expresses a Wrn-targeting gRNA and Cre-recombinase |
| 173626 | Lenti-sgWrn#2/Cre | Expresses a Wrn-targeting gRNA and Cre-recombinase |
| 173627 | Lenti-sgBrca2#1/Cre | Expresses a Brca2-targeting gRNA and Cre-recombinase |
| 173628 | Lenti-sgBrca2#2/Cre | Expresses a Brca2-targeting gRNA and Cre-recombinase |
| 173629 | Lenti-sgCdkn2a#1/Cre | Expresses a Cdkn2a-targeting gRNA and Cre-recombinase |
| 173630 | Lenti-sgCdkn2a#2/Cre | Expresses a Cdkn2a-targeting gRNA and Cre-recombinase |
| 173631 | Lenti-sgCmtr2#1/Cre | Expresses a Cmtr2-targeting gRNA and Cre-recombinase |
| 173632 | Lenti-sgCmtr2#2/Cre | Expresses a Cmtr2-targeting gRNA and Cre-recombinase |
| 173633 | Lenti-sgFat1#1/Cre | Expresses a Fat1-targeting gRNA and Cre-recombinase |
| 173634 | Lenti-sgFat1#2/Cre | Expresses a Fat1-targeting gRNA and Cre-recombinase |
| 173635 | Lenti-sgFbxw7#1/Cre | Expresses a Fbxw7-targeting gRNA and Cre-recombinase |
| 173636 | Lenti-sgFbxw7#2/Cre | Expresses a Fbxw7-targeting gRNA and Cre-recombinase |
| 173637 | Lenti-sgKdm6a#1/Cre | Expresses a Kdm6a-targeting gRNA and Cre-recombinase |
| 173638 | Lenti-sgKdm6a#2/Cre | Expresses a Kdm6a-targeting gRNA and Cre-recombinase |
| 173639 | Lenti-sgKeap1#1/Cre | Expresses a Keap1-targeting gRNA and Cre-recombinase |
| 173640 | Lenti-sgKeap1#2/Cre | Expresses a Keap1-targeting gRNA and Cre-recombinase |
| 173641 | Lenti-sgLrp1b#1/Cre | Expresses a Lrp1b-targeting gRNA and Cre-recombinase |
| 173642 | Lenti-sgLrp1b#2/Cre | Expresses a Lrp1b-targeting gRNA and Cre-recombinase |
| 173643 | Lenti-sgNf2#1/Cre | Expresses a Nf2-targeting gRNA and Cre-recombinase |
| 173644 | Lenti-sgNf2#2/Cre | Expresses a Nf2-targeting gRNA and Cre-recombinase |
| 173645 | Lenti-sgPten#1/Cre | Expresses a Pten-targeting gRNA and Cre-recombinase |
| 173646 | Lenti-sgPten#2/Cre | Expresses a Pten-targeting gRNA and Cre-recombinase |
| 173647 | Lenti-sgPtprd#1/Cre | Expresses a Ptprd-targeting gRNA and Cre-recombinase |
| 173648 | Lenti-sgPtprd#2/Cre | Expresses a Ptprd-targeting gRNA and Cre-recombinase |
| 173649 | Lenti-sgRasa1#1/Cre | Expresses a Rasa1-targeting gRNA and Cre-recombinase |
| 173650 | Lenti-sgRasa1#2/Cre | Expresses a Rasa1-targeting gRNA and Cre-recombinase |
| 173651 | Lenti-sgRbm10#2/Cre | Expresses a Rbm10-targeting gRNA and Cre-recombinase |
| 173652 | Lenti-sgKmt2c#1/Cre | Expresses a Kmt2c-targeting gRNA and Cre-recombinase |
| 173653 | Lenti-sgStk11#2/Cre | Expresses a Stk11-targeting gRNA and Cre-recombinase |
| 173654 | Lenti-sgKmt2c#2/Cre | Expresses a Kmt2c-targeting gRNA and Cre-recombinase |
| 173655 | Lenti-sgTet2#1/Cre | Expresses a Tet2-targeting gRNA and Cre-recombinase |
| 173656 | Lenti-sgTet2#2/Cre | Expresses a Tet2-targeting gRNA and Cre-recombinase |
| 173657 | Lenti-sgTsc1#1/Cre | Expresses a Tsc1-targeting gRNA and Cre-recombinase |
| 173658 | Lenti-sgTsc1#2/Cre | Expresses a Tsc1-targeting gRNA and Cre-recombinase |
| 173659 | Lenti-sgStag2#1/Cre | Expresses a Stag2-targeting gRNA and Cre-recombinase |
| 173660 | Lenti-sgStag2#2/Cre | Expresses a Stag2-targeting gRNA and Cre-recombinase |
| 173661 | Lenti-sgNT.2#2/Cre | Expresses a NT.2-targeting gRNA and Cre-recombinase |
| 173662 | Lenti-sgNT.3#3/Cre | Expresses a NT.3-targeting gRNA and Cre-recombinase |
| 173663 | Lenti-BaeI-Pgk-Cre | Vector with BaeI site to allow cloning of custom sgRNA into vector containing Cre-recombinase |