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A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer.

Cai H, Chew SK, Li C, Tsai MK, Andrejka L, Murray CW, Hughes NW, Shuldiner EG, Ashkin EL, Tang R, Hung KL, Chen LC, Lee SYC, Yousefi M, Lin WY, Kunder CA, Cong L, McFarland CD, Petrov DA, Swanton C, Winslow MM
Cancer Discov. 2021 Feb 19. pii: 2159-8290.CD-20-1325. doi: 10.1158/2159-8290.CD-20-1325. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
173569Lenti-sgArhgap35#1/CreExpresses a Arhgap35-targeting gRNA and Cre-recombinase
173570Lenti-sgArhgap35#2/CreExpresses a Arhgap35-targeting gRNA and Cre-recombinase
173571Lenti-sgArid1a#1/CreExpresses a Arid1a-targeting gRNA and Cre-recombinase
173572Lenti-sgArid1a#2/CreExpresses a Arid1a-targeting gRNA and Cre-recombinase
173573Lenti-sgArid1b#1/CreExpresses a Arid1b-targeting gRNA and Cre-recombinase
173574Lenti-sgArid1b#2/CreExpresses a Arid1b-targeting gRNA and Cre-recombinase
173575Lenti-sgArid2#1/CreExpresses a Arid2-targeting gRNA and Cre-recombinase
173576Lenti-sgArid2#2/CreExpresses a Arid2-targeting gRNA and Cre-recombinase
173577Lenti-sgAtf7ip#1/CreExpresses a Atf7ip-targeting gRNA and Cre-recombinase
173578Lenti-sgAtf7ip#2/CreExpresses a Atf7ip-targeting gRNA and Cre-recombinase
173579Lenti-sgAtm#1/CreExpresses a Atm-targeting gRNA and Cre-recombinase
173580Lenti-sgAtm#2/CreExpresses a Atm-targeting gRNA and Cre-recombinase
173581Lenti-sgBap1#1/CreExpresses a Bap1-targeting gRNA and Cre-recombinase
173582Lenti-sgBap1#2/CreExpresses a Bap1-targeting gRNA and Cre-recombinase
173583Lenti-sgCdkn2c#1/CreExpresses a Cdkn2c-targeting gRNA and Cre-recombinase
173584Lenti-sgCdkn2c#2/CreExpresses a Cdkn2c-targeting gRNA and Cre-recombinase
173585Lenti-sgCic#1/CreExpresses a Cic-targeting gRNA and Cre-recombinase
173587Lenti-sgDnmt3a#1/CreExpresses a Dnmt3a-targeting gRNA and Cre-recombinase
173588Lenti-sgDnmt3a#2/CreExpresses a Dnmt3a-targeting gRNA and Cre-recombinase
173589Lenti-sgDot1l#1/CreExpresses a Dot1l-targeting gRNA and Cre-recombinase
173590Lenti-sgDot1l#2/CreExpresses a Dot1l-targeting gRNA and Cre-recombinase
173591Lenti-sgEp300#1/CreExpresses a Ep300-targeting gRNA and Cre-recombinase
173592Lenti-sgEp300#2/CreExpresses a Ep300-targeting gRNA and Cre-recombinase
173593Lenti-sgErcc4#1/CreExpresses a Ercc4-targeting gRNA and Cre-recombinase
173594Lenti-sgErcc4#2/CreExpresses a Ercc4-targeting gRNA and Cre-recombinase
173595Lenti-sgGata3#1/CreExpresses a Gata3-targeting gRNA and Cre-recombinase
173596Lenti-sgGata3#2/CreExpresses a Gata3-targeting gRNA and Cre-recombinase
173597Lenti-sgKmt2d#1/CreExpresses a Kmt2d-targeting gRNA and Cre-recombinase
173598Lenti-sgKmt2d#2/CreExpresses a Kmt2d-targeting gRNA and Cre-recombinase
173599Lenti-sgLats1#1/CreExpresses a Lats1-targeting gRNA and Cre-recombinase
173600Lenti-sgLats1#2/CreExpresses a Lats1-targeting gRNA and Cre-recombinase
173602Lenti-sgMga#2/CreExpresses a Mga-targeting gRNA and Cre-recombinase
173603Lenti-sgNcoa6#1/CreExpresses a Ncoa6-targeting gRNA and Cre-recombinase
173604Lenti-sgNcoa6#2/CreExpresses a Ncoa6-targeting gRNA and Cre-recombinase
173605Lenti-sgNcor1#1/CreExpresses a Ncor1-targeting gRNA and Cre-recombinase
173606Lenti-sgNcor1#2/CreExpresses a Ncor1-targeting gRNA and Cre-recombinase
173607Lenti-sgNf1#1/CreExpresses a Nf1-targeting gRNA and Cre-recombinase
173608Lenti-sgNf1#2/CreExpresses a Nf1-targeting gRNA and Cre-recombinase
173609Lenti-sgPole#1/CreExpresses a Pole-targeting gRNA and Cre-recombinase
173610Lenti-sgPole#2/CreExpresses a Pole-targeting gRNA and Cre-recombinase
173612Lenti-sgAtrx#1/CreExpresses a Atrx-targeting gRNA and Cre-recombinase
173613Lenti-sgRnf43#1/CreExpresses a Rnf43-targeting gRNA and Cre-recombinase
173614Lenti-sgRnf43#2/CreExpresses a Rnf43-targeting gRNA and Cre-recombinase
173615Lenti-sgSetd2#2/CreExpresses a Setd2-targeting gRNA and Cre-recombinase
173616Lenti-sgAtrx#2/CreExpresses a Atrx-targeting gRNA and Cre-recombinase
173617Lenti-sgSmad4#1/CreExpresses a Smad4-targeting gRNA and Cre-recombinase
173618Lenti-sgSmad4#2/CreExpresses a Smad4-targeting gRNA and Cre-recombinase
173619Lenti-sgSmarca4#1/CreExpresses a Smarca4-targeting gRNA and Cre-recombinase
173620Lenti-sgSmarca4#2/CreExpresses a Smarca4-targeting gRNA and Cre-recombinase
173621Lenti-sgTp53#2/CreExpresses a Tp53-targeting gRNA and Cre-recombinase
173622Lenti-sgTp53#3/CreExpresses a Tp53-targeting gRNA and Cre-recombinase
173623Lenti-sgUbr5#1/CreExpresses a Ubr5-targeting gRNA and Cre-recombinase
173624Lenti-sgUbr5#2/CreExpresses a Ubr5-targeting gRNA and Cre-recombinase
173625Lenti-sgWrn#1/CreExpresses a Wrn-targeting gRNA and Cre-recombinase
173626Lenti-sgWrn#2/CreExpresses a Wrn-targeting gRNA and Cre-recombinase
173627Lenti-sgBrca2#1/CreExpresses a Brca2-targeting gRNA and Cre-recombinase
173628Lenti-sgBrca2#2/CreExpresses a Brca2-targeting gRNA and Cre-recombinase
173629Lenti-sgCdkn2a#1/CreExpresses a Cdkn2a-targeting gRNA and Cre-recombinase
173630Lenti-sgCdkn2a#2/CreExpresses a Cdkn2a-targeting gRNA and Cre-recombinase
173631Lenti-sgCmtr2#1/CreExpresses a Cmtr2-targeting gRNA and Cre-recombinase
173632Lenti-sgCmtr2#2/CreExpresses a Cmtr2-targeting gRNA and Cre-recombinase
173633Lenti-sgFat1#1/CreExpresses a Fat1-targeting gRNA and Cre-recombinase
173634Lenti-sgFat1#2/CreExpresses a Fat1-targeting gRNA and Cre-recombinase
173635Lenti-sgFbxw7#1/CreExpresses a Fbxw7-targeting gRNA and Cre-recombinase
173636Lenti-sgFbxw7#2/CreExpresses a Fbxw7-targeting gRNA and Cre-recombinase
173637Lenti-sgKdm6a#1/CreExpresses a Kdm6a-targeting gRNA and Cre-recombinase
173638Lenti-sgKdm6a#2/CreExpresses a Kdm6a-targeting gRNA and Cre-recombinase
173639Lenti-sgKeap1#1/CreExpresses a Keap1-targeting gRNA and Cre-recombinase
173640Lenti-sgKeap1#2/CreExpresses a Keap1-targeting gRNA and Cre-recombinase
173641Lenti-sgLrp1b#1/CreExpresses a Lrp1b-targeting gRNA and Cre-recombinase
173642Lenti-sgLrp1b#2/CreExpresses a Lrp1b-targeting gRNA and Cre-recombinase
173643Lenti-sgNf2#1/CreExpresses a Nf2-targeting gRNA and Cre-recombinase
173644Lenti-sgNf2#2/CreExpresses a Nf2-targeting gRNA and Cre-recombinase
173645Lenti-sgPten#1/CreExpresses a Pten-targeting gRNA and Cre-recombinase
173646Lenti-sgPten#2/CreExpresses a Pten-targeting gRNA and Cre-recombinase
173647Lenti-sgPtprd#1/CreExpresses a Ptprd-targeting gRNA and Cre-recombinase
173648Lenti-sgPtprd#2/CreExpresses a Ptprd-targeting gRNA and Cre-recombinase
173649Lenti-sgRasa1#1/CreExpresses a Rasa1-targeting gRNA and Cre-recombinase
173650Lenti-sgRasa1#2/CreExpresses a Rasa1-targeting gRNA and Cre-recombinase
173651Lenti-sgRbm10#2/CreExpresses a Rbm10-targeting gRNA and Cre-recombinase
173652Lenti-sgKmt2c#1/CreExpresses a Kmt2c-targeting gRNA and Cre-recombinase
173653Lenti-sgStk11#2/CreExpresses a Stk11-targeting gRNA and Cre-recombinase
173654Lenti-sgKmt2c#2/CreExpresses a Kmt2c-targeting gRNA and Cre-recombinase
173655Lenti-sgTet2#1/CreExpresses a Tet2-targeting gRNA and Cre-recombinase
173656Lenti-sgTet2#2/CreExpresses a Tet2-targeting gRNA and Cre-recombinase
173657Lenti-sgTsc1#1/CreExpresses a Tsc1-targeting gRNA and Cre-recombinase
173658Lenti-sgTsc1#2/CreExpresses a Tsc1-targeting gRNA and Cre-recombinase
173659Lenti-sgStag2#1/CreExpresses a Stag2-targeting gRNA and Cre-recombinase
173660Lenti-sgStag2#2/CreExpresses a Stag2-targeting gRNA and Cre-recombinase
173661Lenti-sgNT.2#2/CreExpresses a NT.2-targeting gRNA and Cre-recombinase
173662Lenti-sgNT.3#3/CreExpresses a NT.3-targeting gRNA and Cre-recombinase
173663Lenti-BaeI-Pgk-CreVector with BaeI site to allow cloning of custom sgRNA into vector containing Cre-recombinase

Antibodies from Article