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Controllable genome editing with split-engineered base editors.
Berrios KN, Evitt NH, DeWeerd RA, Ren D, Luo M, Barka A, Wang T, Bartman CR, Lan Y, Green AM, Shi J, Kohli RM
Nat Chem Biol. 2021 Dec;17(12):1262-1270. doi: 10.1038/s41589-021-00880-w. Epub 2021 Oct 18.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
174696AID'-BE4maxBase Editing
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174697CMV-AID'-seBE4max-IRESSmall-molecule controlled base editing
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174698CMV-A3A-seBE4max-IRESSmall-molecule controlled base editing
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174699CMV-evoA1-seBE4max-IRESSmall-molecule controlled base editing
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174700Lenti-evoA1-BE4maxBase Editing
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174701Lenti-evoA1-seBEN_emptySmall-molecule controlled base editing
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174702Lenti-evoA1-seBECSmall-molecule controlled base editing
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Antibodies from Article