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Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases.
Jang H, Jo DH, Cho CS, Shin JH, Seo JH, Yu G, Gopalappa R, Kim D, Cho SR, Kim JH, Kim HH
Nat Biomed Eng. 2021 Aug 26. pii: 10.1038/s41551-021-00788-9. doi: 10.1038/s41551-021-00788-9.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
176649TS-PE2-NExpresses N-terminus of PE2 in mammalian cells
176650TS-PE2-C-WPREExpresses C-terminus of PE2 in mammalian cells
176901U6-pegRNA-H1-nick sgRNA-mCherryExpresses prime editing guide RNA and guide RNA in mammalian cells
176933pLenti-NG-PE2-BSDExpresses PE2-NG variant in mammalian cells

Antibodies from Article