Tight nanoscale clustering of Fcgamma receptors using DNA origami promotes phagocytosis.
Kern N, Dong R, Douglas SM, Vale RD, Morrissey MA
Elife. 2021 Jun 3;10. pii: 68311. doi: 10.7554/eLife.68311. PubMed Article
Kern N, Dong R, Douglas SM, Vale RD, Morrissey MA
Elife. 2021 Jun 3;10. pii: 68311. doi: 10.7554/eLife.68311. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 176606 | NK66 | To measure Syk intensity in response to ligand clustering using DNA origami |
| 176608 | NK72 | To test macrophage engulfment initiation. Lacks the FcyR chain. |
| 176609 | NK73 | To test bead engulfment of macrophages. |
| 176610 | NK83 | To measure Syk intensity in response to ligand clustering using DNA origami |
| 176611 | NK85 | To minimize dimerization between FcRg transmembrane domains, as this cysteine forms a disulfide bridge between y chains. To manipulate ligand spacing. |
| 176612 | NK88 | To manipulate ligand spacing. |