Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution.
Starr TN, Greaney AJ, Hannon WW, Loes AN, Hauser K, Dillen JR, Ferri E, Farrell AG, Dadonaite B, McCallum M, Matreyek KA, Corti D, Veesler D, Snell G, Bloom JD
Science. 2022 Jun 28:eabo7896. doi: 10.1126/science.abo7896. PubMed Article
Starr TN, Greaney AJ, Hannon WW, Loes AN, Hauser K, Dillen JR, Ferri E, Farrell AG, Dadonaite B, McCallum M, Matreyek KA, Corti D, Veesler D, Snell G, Bloom JD
Science. 2022 Jun 28:eabo7896. doi: 10.1126/science.abo7896. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 184404 | 3019_pETcon-SARS-CoV-2-RBD_E484K | yeast surface display of the SARS-CoV-2 Eta variant RBD |
| 184405 | 3020_pETcon-SARS-CoV-2-RBD_N501Y | yeast surface display of the SARS-CoV-2 Alpha variant RBD |
| 184406 | 3021_pETcon-SARS-CoV-2-RBD_K417N_E484K_N501Y | yeast surface display of the SARS-CoV-2 Beta variant RBD |
| 184407 | 3159_pETcon-SARS-CoV-2-RBD-L452R-T478K | yeast surface display of the SARS-CoV-2 Delta variant RBD |
| 184408 | 3294_pETcon-SARS2-RBD_Omicron-BA1 | yeast surface display of the SARS-CoV-2 Omicron BA.1 variant RBD |
| 184409 | 3322_pETcon_SARS2_Omicron-BA2 | yeast surface display of the SARS-CoV-2 Omicron BA.2 variant RBD |