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CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states.
Leng K, Rose IVL, Kim H, Xia W, Romero-Fernandez W, Rooney B, Koontz M, Li E, Ao Y, Wang S, Krawczyk M, Tcw J, Goate A, Zhang Y, Ullian EM, Sofroniew MV, Fancy SPJ, Schrag MS, Lippmann ES, Kampmann M
Nat Neurosci. 2022 Nov;25(11):1528-1542. doi: 10.1038/s41593-022-01180-9. Epub 2022 Oct 27. PubMed Article

Plasmids from Article

ID Plasmid Purpose
185708pKL100AAVS1 safe-harbor integration of dox-inducible NFIA-SOX9
187889pKL123AAVS1 safe-harbor integration of dox-inducible NFIA-SOX9

Antibodies from Article