A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers.
Koppula P, Lei G, Zhang Y, Yan Y, Mao C, Kondiparthi L, Shi J, Liu X, Horbath A, Das M, Li W, Poyurovsky MV, Olszewski K, Gan B
Nat Commun. 2022 Apr 22;13(1):2206. doi: 10.1038/s41467-022-29905-1. PubMed Article
Koppula P, Lei G, Zhang Y, Yan Y, Mao C, Kondiparthi L, Shi J, Liu X, Horbath A, Das M, Li W, Poyurovsky MV, Olszewski K, Gan B
Nat Commun. 2022 Apr 22;13(1):2206. doi: 10.1038/s41467-022-29905-1. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 186459 | lentiCRISPR v2 sgKEAP1-2 | knock out KEAP1 in mammalian cells |
| 186837 | lentiCRISPR v2 sgKEAP1-3 | knock out KEAP1 in mammalian cells |
| 186838 | lentiCRISPR v2 sgNRF2-3 | knock out NRF2 in mammalian cells |
| 186839 | lentiCRISPR v2 sgNRF2-4 | knock out NRF2 in mammalian cells |