Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry.
Kastenhuber ER, Mercadante M, Nilsson-Payant B, Johnson JL, Jaimes JA, Muecksch F, Weisblum Y, Bram Y, Chandar V, Whittaker GR, tenOever BR, Schwartz RE, Cantley L
Elife. 2022 Mar 23;11. pii: 77444. doi: 10.7554/eLife.77444. PubMed Article
Kastenhuber ER, Mercadante M, Nilsson-Payant B, Johnson JL, Jaimes JA, Muecksch F, Weisblum Y, Bram Y, Chandar V, Whittaker GR, tenOever BR, Schwartz RE, Cantley L
Elife. 2022 Mar 23;11. pii: 77444. doi: 10.7554/eLife.77444. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 187482 | pEGPN | Expression vector - GFP |
| 187483 | pEGPN-ACE2 | Expression vector - ACE2 |
| 187484 | pEGPN-TMPRSS2 | Expression vector - TMPRSS2 |