The GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines.
Smith LJ, Bolsinger MM, Chau KY, Gegg ME, Schapira AHV
Hum Mol Genet. 2022 Sep 20:ddac233. doi: 10.1093/hmg/ddac233. PubMed Article
Smith LJ, Bolsinger MM, Chau KY, Gegg ME, Schapira AHV
Hum Mol Genet. 2022 Sep 20:ddac233. doi: 10.1093/hmg/ddac233. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 188580 | WT GBA pcDNA3.1 | Ectopic expression of wild-type GBA |
| 188581 | E326K GBA pcDNA3.1 | Ectopic expression E326K GBA |
| 188582 | L444P GBA pcDNA3.1 | Ectopic expression L444P GBA |
| 188583 | N370S GBA pcDNA3.1 | Ectopic expression N370S GBA |