Addgene: A general chemical principle for creating closure-stabilizing integrin inhibitors.

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A general chemical principle for creating closure-stabilizing integrin inhibitors.
Lin FY, Li J, Xie Y, Zhu J, Huong Nguyen TT, Zhang Y, Zhu J, Springer TA
Cell. 2022 Sep 15;185(19):3533-3550.e27. doi: 10.1016/j.cell.2022.08.008. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
189796	pD2529-CAG-aIIb	Expression of full length human integrin aIIb
189797	pD2529-CAG-b3	Expression of full length human integrin beta 3
189798	pD2529-CAG-b3 N305T	Expression of full length human integrin beta 3 with N305T
194008	pSpCas9n(BB)-2A-puro-aV guide A	For CRISPR knockout of integrin alphaV
194009	pSpCas9n(BB)-2A-puro-aV guide B	For CRISPR knockout of integrin alphaV
194010	pSpCas9n(BB)-2A-puro-a5 guide A	For CRISPR knockout of integrin alpha5
194011	pSpCas9n(BB)-2A-puro-a5 guide B	For CRISPR knockout of integrin alpha5

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