Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate efflux.
Luethi D, Maier J, Rudin D, Szollosi D, Angenoorth TJF, Stankovic S, Schittmayer M, Burger I, Yang JW, Jaentsch K, Holy M, Das AK, Brameshuber M, Camacho-Hernandez GA, Casiraghi A, Newman AH, Kudlacek O, Birner-Gruenberger R, Stockner T, Schutz GJ, Sitte HH
Commun Biol. 2022 Nov 17;5(1):1259. doi: 10.1038/s42003-022-04210-1. PubMed Article
Luethi D, Maier J, Rudin D, Szollosi D, Angenoorth TJF, Stankovic S, Schittmayer M, Burger I, Yang JW, Jaentsch K, Holy M, Das AK, Brameshuber M, Camacho-Hernandez GA, Casiraghi A, Newman AH, Kudlacek O, Birner-Gruenberger R, Stockner T, Schutz GJ, Sitte HH
Commun Biol. 2022 Nov 17;5(1):1259. doi: 10.1038/s42003-022-04210-1. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 193364 | mGFP-hNET | expression of human norpinephrine transporter tagged with monomeric GFP at the N-terminus in mammalian cells |
| 193365 | mGFP-hNET-A457P | expression of mutated human norpinephrine transporter tagged with monomeric GFP at the N-terminus in mammalian cells |
| 193366 | mGFP-hNET-R121A/K334A/R440A | expression of mutated human norpinephrine transporter tagged with monomeric GFP at the N-terminus in mammalian cells |