Lysosomal positioning regulates Rab10 phosphorylation at LRRK2(+) lysosomes.
Kluss JH, Beilina A, Williamson CD, Lewis PA, Cookson MR, Bonet-Ponce L
Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2205492119. doi: 10.1073/pnas.2205492119. Epub 2022 Oct 18. PubMed Article
Kluss JH, Beilina A, Williamson CD, Lewis PA, Cookson MR, Bonet-Ponce L
Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2205492119. doi: 10.1073/pnas.2205492119. Epub 2022 Oct 18. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 193582 | LYSO-LRRK2 | Expresses human full-length LRRK2 with a lysosomal targeting sequence from LAMTOR1 (1-39aa) and 3xFLAG on the N-terminus |
| 193583 | EE-LRRK2 | Expresses full-length LRRK2 with FYVE-CC2 domains from HRS and 3xFLAG on the N-terminus |
| 193584 | 3xFLAG-FKBP-LRRK2 | Expresses human full-length LRRK2 with FKBP domain and 3xFLAG situated at the N-terminus |