Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Hunkeler M, Jin CY, Fischer ES
Science. 2023 Mar 17;379(6637):1105-1111. doi: 10.1126/science.ade5750. Epub 2023 Feb 9.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
197967pDARMO_CMVT_3xFLAG_BIRC6Mammalian cell expression of wt 3xFLAG-BIRC6
Loading...
197968pDARMO_CMVT_3xFLAG_BIRC6_BIRmutMammalian cell expression of 3xFLAG-BIRC6_BIRmut
Loading...
197969pDARMO_CMVT_3xFLAG_BIRC6_delta(Helix)Mammalian cell expression of 3xFLAG-BIRC6_delta(Helix)
Loading...
197970pDARMO_CMVT_3xFLAG_BIRC6_delta(Helix)_BIRmutMammalian cell expression of 3xFLAG-BIRC6_delta(Helix)/BIRmut
Loading...
197971pDARMO_CMVT_N_FLAG_UBA6Mammalian cell expression of FLAG-UBA6
Loading...
197972pDARMO_CMVT_N_Strep_BIRC6Mammalian cell expression of wt Strep-BIRC6
Loading...
197973pDEST_CMV_N_Flag_BIRC6Mammalian cell expression of wt FLAG-BIRC6
Loading...
197974pDONR223_BIRC6Entry clone for wt BIRC6
Loading...
197975pET-20b_HtrA2(delta(133))_S306A_6HisE. coli expression of HtrA2(delta133)-6His
Loading...
197976pNIC-Bio2_SMAC(delta(55))_9HisE. coli expression of SMAC(delta(55))-9His
Loading...
197977pNIC-Bio2_SMAC(delta(55))_Cys_9HisE. coli expression of SMAC(delta(55))_Cys-9His
Loading...
197978pNIC-Bio2_MVPI_SMAC(delta(55))_9HisE. coli expression of MVPI-SMAC(delta(55))_9His
Loading...

Antibodies from Article