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Optimized whole-genome CRISPR interference screens identify ARID1A-dependent growth regulators in human induced pluripotent stem cells.

Usluer S, Hallast P, Crepaldi L, Zhou Y, Urgo K, Dincer C, Su J, Noell G, Alasoo K, El Garwany O, Gerety SS, Newman B, Dovey OM, Parts L
Stem Cell Reports. 2023 May 9;18(5):1061-1074. doi: 10.1016/j.stemcr.2023.03.008. Epub 2023 Apr 6. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
260206pCS2-iREP-GFP-PGK-BFP-U6-gRNA-irep Plasmid encoding for GFP and BFP with a CRISPRi gRNA targeting GFP to validate CRISPRi activity
260207pCS2-iREP-GFP-PGK-BFP-U6-gRNA-mockPlasmid encoding for GFP and BFP with a non-targeting CRISPRi gRNA to validate CRISPRi activity

Antibodies from Article