Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin.
Dekan Z, Kremsmayr T, Keov P, Godin M, Teakle N, Durrauer L, Xiang H, Gharib D, Bergmayr C, Hellinger R, Gay M, Vilaseca M, Kurzbach D, Albericio F, Alewood PF, Gruber CW, Muttenthaler M
Chem Sci. 2021 Feb 4;12(11):4057-4062. doi: 10.1039/d0sc05501h. PubMed Article
Dekan Z, Kremsmayr T, Keov P, Godin M, Teakle N, Durrauer L, Xiang H, Gharib D, Bergmayr C, Hellinger R, Gay M, Vilaseca M, Kurzbach D, Albericio F, Alewood PF, Gruber CW, Muttenthaler M
Chem Sci. 2021 Feb 4;12(11):4057-4062. doi: 10.1039/d0sc05501h. PubMed Article
Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
208913 | OTR untagged | encodes the human oxytocin receptor, without any tags |
208914 | V1aR untagged | encodes the human vasopressin receptor 1a, without any tags |