Engineering TALE-linked deaminases to facilitate precision adenine base editing in mitochondrial DNA.
Cho SI, Lim K, Hong S, Lee J, Kim A, Lim CJ, Ryou S, Lee JM, Mok YG, Chung E, Kim S, Han S, Cho SM, Kim J, Kim EK, Nam KH, Oh Y, Choi M, An TH, Oh KJ, Lee S, Lee H, Kim JS
Cell. 2024 Jan 4;187(1):95-109.e26. doi: 10.1016/j.cell.2023.11.035. PubMed Article
Cho SI, Lim K, Hong S, Lee J, Kim A, Lim CJ, Ryou S, Lee JM, Mok YG, Chung E, Kim S, Han S, Cho SM, Kim J, Kim EK, Nam KH, Oh Y, Choi M, An TH, Oh KJ, Lee S, Lee H, Kim JS
Cell. 2024 Jan 4;187(1):95-109.e26. doi: 10.1016/j.cell.2023.11.035. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 212949 | TALED_ Left-mouse-mtRnr1_A1555G-8e-E1347A | Expresses TALED_ Left-mouse-mtRnr1_A1555G-8e-E1347A in mammalian cells |
| 212950 | TALED_Left-Cox3.1-1397N. | Expresses TALED_Left-Cox3.1-1397N. in mammalian cells |
| 212951 | TALED_Left-mouse-ATP6-1397N. | Expresses TALED_Left-mouse-ATP6-1397N in mammalian cells |
| 212952 | TALED_Left-ND6-1397N | Expresses TALED_Left-ND6-1397N in mammalian cells |
| 212953 | TALED_Right-Cox3.1-1397C-AD. | ExpressesTALED_Right-Cox3.1-1397C-AD in mammalian cells |
| 212954 | TALED_Right-mouse-ATP6-1397C-AD | Expresses TALED_Right-mouse-ATP6-1397C-AD in mammalian cells |
| 212956 | TALED_Right-ND6-1397C-AD | Expresses TALED_Right-ND6-1397C-AD in mammalian cells |