LMP1 and EBNA2 constitute a minimal set of EBV genes for transformation of human B cells.
Zhang J, Sommermann T, Li X, Gieselmann L, de la Rosa K, Stecklum M, Klein F, Kocks C, Rajewsky K
Front Immunol. 2023 Dec 19;14:1331730. doi: 10.3389/fimmu.2023.1331730. eCollection 2023.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 220350 | MSCV-LMP1-IRES-GFP | Expresses EBV latent gene LMP1 in mammalian cells |
| 220351 | MSCV-LMP1-IRES-mCherry | Expresses EBV latent gene LMP1 in mammalian cells |
| 220352 | MSCV-LMP2A-IRES-GFP | Expresses EBV latent gene LMP2A in mammalian cells |
| 220353 | MSCV-LMP2A-IRES-mCherry | Expresses EBV latent gene LMP2A in mammalian cells |
| 220354 | MSCV-opEBNA2-IRES-GFP | Expresses EBV latent gene EBNA2 in mammalian cells (EBNA2 coding sequence was optimised for expression and carries a C-terminal 3xHA-tag) |
| 220355 | MSCV-opEBNA2-IRES-mCherry | Expresses EBV latent gene EBNA2 in mammalian cells (EBNA2 coding sequence was optimised for expression) |