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Glutamylation of Npm2 and Nap1 acidic disordered regions increases DNA mimicry and histone chaperone efficiency.

Lorton BM, Warren C, Ilyas H, Nandigrami P, Hegde S, Cahill S, Lehman SM, Shabanowitz J, Hunt DF, Fiser A, Cowburn D, Shechter D
iScience. 2024 Mar 8;27(4):109458. doi: 10.1016/j.isci.2024.109458. eCollection 2024 Apr 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
258226pRUTH5_XlH2AE. coli expression of Xenopus laevis H2A with an N-terminal cleavable His tag
258227pRUTH5_XlH2BE. coli expression of Xenopus laevis H2B with an N-terminal cleavable His tag
258228pRUTH5_XlH3E. coli expression of Xenopus laevis H3.2 with an N-terminal cleavable His tag
258229pRUTH5-GST-XlH1AE. coli expression of Xenopus laevis H1A with an N-terminal cleavable His-GST tag and a C-terminal Strep-tag II
258230pGEX6P-GST-XlH1ME. coli expression of Xenopus laevis H1M with an N-terminal cleavable His-GST tag and a C-terminal Strep-tag II
258231pRUTH5_XlH2A-StrepIIE. coli expression of Xenopus laevis H2A with an N-terminal cleavable His tag and C-terminal StrepII tag and a C-terminal Strep-tag II
258233pRUTH5_Xl-NPM2E. coli expression of Xenopus laevis full length NPM2 with an N-terminal cleavable His tag
258234pRUTH5_Xl-NPM2-CoreE. coli expression of Xenopus laevis NPM2 core with an N-terminal cleavable His tag
258235pRUTH5_Xl-NPM2-Core+A2E. coli expression of Xenopus laevis NPM2 core + A2 with an N-terminal cleavable His tag
258236pRUTH5-GST_Xl-NPM2-CtermE. coli expression of Xenopus laevis NPM2 Cterm (past A3) with an N-terminal cleavable His-GST tag
258239pRUTH5_Xl-Nap1 delta A3E. coli expression of Xenopus laevis Nap1L1.L delta A3 with an N-terminal cleavable His tag
258240pRUTH5_Xl-Nap1 coreE. coli expression of Xenopus laevis Nap1L1.L core domain with an N-terminal cleavable His tag

Antibodies from Article