CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning.
Teter OM, McQuade A, Hagan V, Liang W, Drager NM, Sattler SM, Holmes BB, Castillo VC, Papakis V, Leng K, Boggess S, Nowakowski TJ, Wells J, Kampmann M
Mol Psychiatry. 2025 Sep;30(9):4176-4193. doi: 10.1038/s41380-025-02997-z. Epub 2025 Apr 6.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 234942 | pOT056 | Constitutive expression of Gamillus fluorescent protein |
| 234943 | pOT020 | Constitutive expression of synaptophysin linked to Gamillus fluorescent protein |
| 234944 | pKL078 | Constitutive expression of membrane receptor Lck linked to mNeonGreen fluorescent protein and a nuclear localized mTagBFP2 fluorescent protein |