RBBP6 anchors pre-mRNA 3' end processing to nuclear speckles for efficient gene expression.
Yoon Y, Bournique E, Soles LV, Yin H, Chu HF, Yin C, Zhuang Y, Liu X, Liu L, Jeong J, Yu C, Valdez M, Tian L, Huang L, Shi X, Seelig G, Ding F, Tong L, Buisson R, Shi Y
Mol Cell. 2025 Feb 6;85(3):555-570.e8. doi: 10.1016/j.molcel.2024.12.016. Epub 2025 Jan 10.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 253988 | pcDNA3.1-copGFP-RBBP6 NTD | Transient expression of RBBP6 NTD |
| 253989 | pcDNA3.1-copGFP-RBBP6 NTD+IDR4 | Transient expression of RBBP6 NTD and IDR4 |
| 253991 | pET-51b(+)-twinstrep-RBBP6 NTD | Expressing RBBP6 variants in bacteria for protein purification |
| 253992 | pET-51b(+)-twinstrep-RBBP6 NTD+IDR4 | Expressing RBBP6 variants in bacteria for protein purification |
| 253994 | pET-51b(+)-twinstrep-mEGFP-SRRM2 UPR3 | Expressing SRRM2 undeca-amino acid repeat regions (UPR) in bacteria for protein purification |