Membranes arrest the coarsening of mitochondrial condensates in human cells.
Aththawala Gedara SVBD, Penna ST, Feric M
Commun Biol. 2026 Apr 23. doi: 10.1038/s42003-026-10085-3.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 241146 | MTS-DDX28(IDR)-mCh-CRY2olig | Expresses mt-optoIDR with DDX28 (1-127 aa) to optogenetically induce biomolecular condensates within mitochondrial matrix in living cells. |
| 254613 | MTS-TWINKLE(IDR)-mCh-CRY2olig | Expresses mt-optoIDR with TWINKLE (1-170 aa) to optogenetically induce biomolecular condensates within mitochondrial matrix in living cells. |
| 254614 | MTS-GRSF1(IDR)-mCh-CRY2olig | Expresses mt-optoIDR with GRSF1(1-150 aa) to optogenetically induce biomolecular condensates within mitochondrial matrix in living cells. |
| 254615 | MTS-mCh-CRY2olig | negative control for mt-optoIDR that lacks any IDRs |
| 254616 | MTS-DDX28(IDR)-mCh | negative control for mt-optoIDR that lacks light activation domain |