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iBiT: A vector system allowing stable genome integration and scalable expression of NanoLuc fusion proteins to monitor dynamic protein-protein interactions in intact cells.

Dreute J, Schmitz ML
Plasmid. 2026 May 23;135:102772. doi: 10.1016/j.plasmid.2026.102772. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
245343pAAVS-iBiT-Lg-MCS-BSDCRISPR/Cas9 mediated integration of the iBiT-system (doxycycline inducible NanoBiT) into the AAVS1 safe-harbor locus on chromosome 19
245344pAAVS-iBiT-MCS-Lg-BSDCRISPR/Cas9 mediated integration of the iBiT-system (doxycycline inducible NanoBiT) into the AAVS1 safe-harbor locus on chromosome 19
245345pAAVS-iBiT-MCS-Sm-PuroCRISPR/Cas9 mediated integration of the iBiT-system (doxycycline inducible NanoBiT) into the AAVS1 safe-harbor locus on chromosome 19
245346pAAVS-iBiT-Sm-MCS-PuroCRISPR/Cas9 mediated integration of the iBiT-system (doxycycline inducible NanoBiT) into the AAVS1 safe-harbor locus on chromosome 19
245347pAAVS-iBiT-p62(iso1)-Lg-BSD(Positive control for protein-protein interaction) CRISPR/Cas9 mediated integration of the iBiT-system (doxycycline inducible NanoBiT) into the AAVS1 safe-harbor locus on chromosome 19
245348pAAVS-iBiT-p62(iso2)-Sm-Puro(Positive control for protein-protein interaction) CRISPR/Cas9 mediated integration of the iBiT-system (doxycycline inducible NanoBiT) into the AAVS1 safe-harbor locus on chromosome 19

Antibodies from Article