Feature-specific threat coding in lateral septum guides defensive action.
Bhatti Mazo DL, Berger MZC, Pasqualini AL, Wu SJ, Reid CM, Brito SI, Qiu S, Levitt P, Harwell CC, Anthony TE, Fishell G
Nature. 2026 Aug;656(8127):415-424. doi: 10.1038/s41586-026-10520-9. Epub 2026 May 20.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 248662 | pAAV_EF1a-FLEx(FRT)-stGtACR2:eGFP (soma-targeted) | Expresses a soma-targeted GtACR2 in Flp-expressing cells under the EF1a promoter for neuronal inhibition. |
| 248664 | pAAV_CAG(del)-FLEx(loxP)-eYFP(nuclear)-2A-N2cG | Helper virus for monosynaptic tracing; Expresses nuclear eYFP and Rabies Glycoprotein (G) of CVS-N2c strain in Cre-expressing cells under the CAG promoter. |
| 248665 | pAAV_CAG(del)--FLEx(loxP)-splitTVA:HA | Helper virus for monosynaptic tracing; Expresses TVA and an HA tag in Cre-expressing cells under the CAG promoter. To be co-injected with Rabies Glycoprotein (G) viruses. |
| 248667 | pAAV_CAG(del)-FLEx(loxP)-ARch3.0:EYFP | Expresses Archaerhodopsin3 tagged to eYFP in Cre-expressing cells under the CAG promoter for neuronal inhibition. |
| 252530 | pAAV_EF1a-FLEx(FRT)-GCaMP8m | Expresses the genetically encoded calcium indicator GCaMP8m in Flp-expressing cells under the EF1a promoter for calcium imaging. |