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Pooled CRISPRi screening reveals fungal-specific drug target candidates.

Wensing LF, Despres PC, Francis D, Fogal M, Hendriks A, Gervais NC, Fikry C, Adamu Bukari AR, Gerstein AC, Cuomo CA, Shapiro RS
Nat Microbiol. 2026 May 11. doi: 10.1038/s41564-026-02356-w. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
250493pRS479Regulatable CRISPRi plasmid for use in Candida albicans. Contains dCas9-Mxi1 controlled by a tetO promoter, NEUT5L integration site and the sgRNA cloning site

Antibodies from Article