Directed evolution of Lantern enables rapid RNA and protein proximity labeling.
Fang Y, Ren Z, Zheng F, Wang R, Zhao S, Zhang Y, Wang W, Li C, Liu-Yang L, Lin C, Liu J, Zou P
Nat Chem Biol. 2026 Sep 7. doi: 10.1038/s41589-026-02313-y.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 250916 | pLX304-Lantern-Sec61β | Expresses Lantern fused to Sec61β in mammalian cells for targeting to the ER |
| 250917 | pLX304-Lantern-MAVS | Expresses Lantern fused to the C-terminal 31 amino acids of MAVS in mammalian cells for targeting to the outer mitochondrial membrane |
| 250918 | pLX304-G3BP1-Lantern | Expresses Lantern fused to G3BP1 in mammalian cells for targeting to stress granules |
| 250919 | pLX304-Lantern-HaloTag-NES | Expresses Lantern in mammalian cytosol |
| 250920 | pLX304-mito-Lantern | Expresses Lantern fused to the N-terminal 23 amino acid residues of human COX4 in mammalian cells |
| 250922 | pcDNA3.1-mito-Lantern | Expresses Lantern fused to the N-terminal 23 amino acid residues of human COX4 in mammalian cells |