A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs.
Murai S, Yamaguchi Y, Shirasaki Y, Yamagishi M, Shindo R, Hildebrand JM, Miura R, Nakabayashi O, Totsuka M, Tomida T, Adachi-Akahane S, Uemura S, Silke J, Yagita H, Miura M, Nakano H
Nat Commun. 2018 Oct 26;9(1):4457. doi: 10.1038/s41467-018-06985-6.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 256103 | pT2K-CAGGSv3-murine SMART | For real-time monitoring of necroptosis execution in murine cells; does not work in human cells. |
| 256109 | pT2K-CAGGSv3-human SMART | For real-time monitoring of necroptosis execution in human cells; does not work in murine cells. |
| 256110 | pT2K-CAGGSv3-murine HMGB1-mCherry | For real-time monitoring of HMGB1 release at the single-cell level. |
| 256111 | pT2K-CAGGSv3-murine histone H3-mCherry | For real-time monitoring of histone H3 release at the single-cell level. |