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A genetically encoded fluorescent sensor for monitoring spatiotemporal prostaglandin E2 dynamics in vivo.

Wang L, Yang Y, Deng F, Yan Y, Wang H, Li B, Wan J, Li Y
Neuron. 2026 Jun 3;114(11):1922-1934.e5. doi: 10.1016/j.neuron.2026.01.030. Epub 2026 Mar 13. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
251353pDisplay-GRAB_PGE2-1.0-IRES-mCherry-CAAXExpress the PGE2 sensor GRAB_PGE2-1.0 in mammalian cells
251354pDisplay-GRAB_PGE2mut-IRES-mCherry-CAAXExpress the PGE2-insensitive control sensor GRAB_PGE2mut in mammalian cells
251355pAAV-EF1α-GRAB_PGE2-1.0Express the PGE2 sensor GRAB_PGE2-1.0 in mammalian cells
251356pAAV-EF1α-GRAB_PGE2mutExpress the PGE2-insensitive control sensor GRAB_PGE2mut in mammalian cells

Antibodies from Article