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Triazine Thiols Decrease Apolipoprotein B Secretion From Hepatocytes Through Inhibition of Human Carboxylesterase 1.

Blaszkiewicz J, Jiang YL, Liu JT, Martinez-Morant C, Dearth T, van Altena C, Lamprecht MP, Kappler C, Lee MH, Bethard JR, Ball LE, Duncan SA
Cell Mol Gastroenterol Hepatol. 2026;20(8):101796. doi: 10.1016/j.jcmgh.2026.101796. Epub 2026 Apr 29. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
252212pTET-tight-CES1WTDoxycycline-inducible expression of wild-type carboxylesterase 1 (CES1)
252213pTET-tight-CES1C390KDoxycycline-inducible expression of carboxylesterase 1 (CES1) with the cysteine 390 residue replaced with a lysine
252214px459-sgCES1Used to generate CES1 knockout, targets exon 2

Antibodies from Article