Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects.
Pendyala S, Partington K, Bradley N, McEwen AE, Straub G, Kim HJ, Fayer S, Holmes DL, Sitko KA, Vandi AJ, Powell RL, Friedman CE, McDermot E, Kishore N, Roth FP, Rubin AF, Yang KC, Starita LM, Noble WS, Fowler DM
bioRxiv [Preprint]. 2025 Jul 5:2025.07.03.663081. doi: 10.1101/2025.07.03.663081.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 252243 | PB-circBC-UCOE-EF1a-mEGFP(NTag)-IRES-PuroR-WPRE | VIS-seq expression plasmid |
| 252244 | PB-circBC-UCOE-EF1a-mEGFP(CTag)-IRES-PuroR-WPRE | VIS-seq expression plasmid |
| 252245 | PB-circBC-UCOE-CAG-mEGFP(NTag)-IRES-PuroR-WPRE | VIS-seq expression plasmid |