U2AF1 mutations rescue deleterious exon skipping induced by KRAS mutations.
Walter DM, Cho K, Sivakumar S, Denney D, Lee IT, Dohlman AB, Heinz JM, Shurberg E, Jiang KX, Gupta AA, Frampton GM, Meyerson M
bioRxiv [Preprint]. 2025 Sep 18:2025.03.21.644128. doi: 10.1101/2025.03.21.644128.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 256552 | pLX301-U2AF1-WT-FLAG | Lentiviral vector for expression of FLAG-tagged U2AF1 in mammalian cells |
| 256553 | pLX301-U2AF1-S34F-FLAG | Lentiviral vector for expression of FLAG-tagged U2AF1 S34F in mammalian cells |
| 256554 | pLX301-U2AF1-I24T-FLAG | Lentiviral vector for expression of FLAG-tagged U2AF1 I24T in mammalian cells |
| 256555 | pSpliceExpress-KRAS-Exon2 | pSpliceExpress splicing reporter to measure inclusion or skipping of exon 2 of KRAS |
| 256556 | pSpliceExpress-KRAS-Exon3 | pSpliceExpress splicing reporter to measure inclusion or skipping of exon 3 of KRAS |