mRNA 3' UTRs chaperone intrinsically disordered regions to control protein activity.
Luo Y, Zhong Y, Basu S, Wu MC, Mayr C
Cell. 2026 Jun 8:S0092-8674(26)00576-3. doi: 10.1016/j.cell.2026.05.017.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 255431 | pcDNA3.1-puro-mycProm-EGFP-MYC-NU | Mammalian expression of GFP-tagged MYC, under the control of its own promoter |
| 255432 | pcDNA3.1-puro-mycProm-EGFP-MYC-U | GFP-tagged MYC with its own 3'UTR |
| 255434 | pCMV-HA-KDM6B-U | Mammalian expression of HA-tagged human JMJD3 with its own 3'UTR |
| 255435 | pCMV-HA-NLS-KDM6B-IDRdel-NU | Mammalian expression of HA-tagged human JMJD3 lacking its IDR |
| 255436 | pCMV-HA-FOXP2-NU | Mammalian expression of HA- and FLAG-tagged human FOXP2 |
| 255438 | pCMV-HA-SSRP1-NU | Mammalian expression of HA-tagged human SSRP1 |
| 255439 | pCMV-HA-SSRP1-U | HA-tagged human SSRP1 with its own 3'UTR |
| 255440 | pCMV-HA-SF3B4-NU | Mammalian expression of HA-tagged human SF3B4 |
| 255441 | pCMV-HA-SF3B4-U | HA-tagged human SF3B4 with its own 3'UTR |
| 255442 | pCMV-HA-EIF3I-NU | Mammalian expression of HA-tagged human EIF3I |
| 255443 | pCMV-HA-EIF3I-U | HA-tagged human EIF3I with its own 3'UTR |
| 255444 | pCMV-HA-SSBP4-NU | Mammalian expression of HA-tagged human SSBP4 |
| 255445 | pCMV-HA-SSBP4-U | HA-tagged human SSBP4 with its own 3'UTR |
| 255446 | pCMV-HA-DHPS-NU | Mammalian expression of HA-tagged human DHPS |
| 255447 | pCMV-HA-DHPS-U | HA-tagged human DHPS with its own 3'UTR |
| 255448 | pCMV-HA-RACK1-NU | Mammalian expression of HA-tagged human RACK1 |
| 255449 | pCMV-HA-RACK1-U | HA-tagged human RACK1 with its own 3'UTR |
| 255450 | pCMV-HA-ENO1-NU | Mammalian expression of HA-tagged human ENO1 |
| 255451 | pCMV-HA-ENO1-U | HA-tagged human ENO1 with its own 3'UTR |