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Dual E3 ligase recruitment by monovalent degraders enables redundant and tuneable degradation of SMARCA2/4

Spiteri VA, Segal D , Correa-Sáez A, Iso K, Casement R, Muñoz i Ordoño M, Nakasone MA, Sathe G, Schätz C, Peters HE, Doward M, Kainacher L, Cowan AD, Ciulli A, Winter GE
bioRxiv 2025.08.04.668513 (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
25393912xHis-SUMO-SMARCA4(1448-1568) Brd onlyfor Bacterial Protein Overexpression

Antibodies from Article