NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome.
Coombs JR, Zamoshnikova A, Holley CL, Maddugoda MP, Teo DET, Chauvin C, Poulin LF, Vitak N, Ross CM, Mellacheruvu M, Coll RC, Heinz LX, Burgener SS, Emming S, Chamaillard M, Boucher D, Schroder K
Sci Signal. 2024 Jan 23;17(820):eabg8145. doi: 10.1126/scisignal.abg8145. Epub 2024 Jan 23.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 254942 | pEF6_hNLRP10-mCherry (KS300) | Complete human NLRP10 (UniProt Q86W26) with a C-terminal mCherry tag in pEF6 for mammalian and bacterial expression. |