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DROSHA Regulates Mesenchymal Gene Expression in Wilms Tumor.

Tiburcio PDB, Desai K, Kim J, Zhou Q, Guo L, Xiao X, Zhou L, Yuksel A, Catchpoole DR, Amatruda JF, Xu L, Chen KS
Mol Cancer Res. 2024 Aug 2;22(8):711-720. doi: 10.1158/1541-7786.MCR-23-0930. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
255340pLV hU6-sgNT2-2-hUbC-dCas9-KRAB-T2a-PuroCRISPRi nontargeting control
255342pLV hU6-sgDROSHA-3-hUbC-dCas9-KRAB-T2a-PuroCRISPRi targeting DROSHA
255343pLV hU6-sgDROSHA-7-hUbC-dCas9-KRAB-T2a-PuroCRISPRi targeting DROSHA
255344pLV hU6-sgDICER1-1-hUbC-dCas9-KRAB-T2a-PuroCRISPRi targeting DICER1
255345pLV hU6-sgDICER1-4-hUbC-dCas9-KRAB-T2a-PuroCRISPRi targeting DICER1

Antibodies from Article