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OptoTAT reveals microtubule acetylation as a rapid trigger for GEF-H1-mediated cell migration.

Deb Roy A, Gonzalez CS, Stanislauskas M, Shahid F, Yadav E, Rezek J, Inoue T
J Cell Biol. 2026 May 4;225(5):e202508095. doi: 10.1083/jcb.202508095. Epub 2026 Mar 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
255915mCherry-Paxillinfor use with optoTAT system
255916mVenus-αTAT1for use with optoTAT system
255917mVenus-αTAT1(D157N)for use with optoTAT system
255918lenti-mVenus-αTAT1for use with optoTAT system
255920mCherry-MRLCfor use with optoTAT system
255922mVenus-optoTATfor use with optoTAT system
255923mCherry-optoTATfor use with optoTAT system
255925miRFP703-optoTAT(D157N)for use with optoTAT system
255926lenti-mCherry-MRLCfor use with optoTAT system
255929mCherry-GEF-H1for use with optoTAT system
255930mCherry-GEF-H1(C53R)for use with optoTAT system
255931lenti-mCherry-GEF-H1(C53R)for use with optoTAT system

Antibodies from Article