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Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles.

Karabova MK, Del Ser-Badia A, Hedegaard A, Washer SJ, Baykam Z, O'Brien DP, Vendrell I, Hester SS, Fischer R, Johnson E, Melia CE, Matthews-Palmer TRS, Matadeen R, Santambrogio A, Metrick MA 2nd, Vendruscolo M, Keeling S, Cheam KAX, McEwan WA, Kosik KS, Day TA, James WS, Cowley SA
Alzheimers Dement. 2026 Apr;22(4):e71337. doi: 10.1002/alz.71337. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
249347pETM11-Sumo3-TauWT2N4RExpresses full-length(2N4R) human wild-type tau in E. coli. For protein purification purposes.

Antibodies from Article