PHIP suppresses NuRD to enable the growth of SWI/SNF-mutant cancers.
Malone HA, Myers JA, Gruss EG, Morgan MA, Friske JD, McCarty TC, Navarro JJ, Robinson S, Halliburton RL, Kietlinska SJ, De Luna Vitorino FN, Hansen BS, Pruett-Miller SM, Garcia BA, Roussel MF, Partridge JF, Roberts CWM
Nat Commun. 2026 Apr 7;17(1):2877. doi: 10.1038/s41467-026-70699-3.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 259656 | XLone-Strep-tag-2xHA-PHIP | PiggyBac expression for doxycycline inducible expression of Strep-tag and HA-tagged PHIP |
| 259657 | XLone-Strep-tag-2xHA-delta-H-Box-PHIP | PiggyBac expression for doxycycline inducible expression of Strep-tag and HA-tagged PHIP [H-Box deletion mutant] |
| 259659 | LentiCRISPR-puro-sgPHIP1 | All-in-one lentiviral transfer vector designed to deliver and express both Cas9 nuclease and sgRNA targeting PHIP (sgPHIP1) |
| 259660 | LentiCRISPR-puro-sgPHIP2 | All-in-one lentiviral transfer vector designed to deliver and express both Cas9 nuclease and sgRNA targeting PHIP (sgPHIP2) |
| 259662 | LentiCRISPR-mCherry-sgPHIP2 | All-in-one lentiviral vector designed to deliver and express both Cas9 nuclease and sgRNA targeting PHIP (sgPHIP2), with added feature for monitoring (expression of mCherry) |
| 259663 | LentiCRISPR-mCherry-sgAAVS1 | All-in-one lentiviral vector designed to deliver and express both Cas9 nuclease and sgRNA targeting AAVS1 (sgAAVS1), with added feature for monitoring (expression of mCherry) |
| 259664 | LentiCRISPR-mCherry-sgLacZ | All-in-one lentiviral vector designed to deliver and express both Cas9 nuclease and sgRNA targeting LacZ (sgLacZ), with added feature for monitoring (expression of mCherry) |