The E3 ligase MKRN2 prevents DRiP accumulation in stress granules and maintains granulostasis.
Amzallag E, Danino YM, Secco V, Carra S, Hornstein E
EMBO Rep. 2026 Jun 15. doi: 10.1038/s44319-026-00832-2.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 257245 | eGFP-MKRN2-pcDNA4/TO | Expresses eGFP-MKRN2 under tetracycline inducible promoter. |
| 257246 | eGFP-MKRN2-dRING-pcDNA4/TO | Expresses eGFP-MKRN2 with mutated RING domain under tetracycline inducible promoter. All cysteine and histidine residues in the RING domain were mutated to alanine. |