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Lentiviral single-cell MPRA of synthetic enhancers reveals motif affinity-based encoding of cell state specificity.

Ruhle J, Fromel R, Martinez AB, Szu-Tu C, Bowness J, Velten L
Genome Biol. 2026 Jul 14. doi: 10.1186/s13059-026-04186-9. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
257694pLS-hu6-EGFP-sc-lentiMPRALentivirus single-cell reporter assay plasmid that contains an hu6 promoter and an EGFP reporter gene to insert barcoded gRNAs and barcoded cis-regulatory elements.

Antibodies from Article