Skip to main content

Structure, Biosynthesis, and Bioactivity of Nostolysamides.

Weir E, Anterola I, van der Donk WA
Biochemistry. 2026 May 5;65(9):1578-1591. doi: 10.1021/acs.biochem.6c00103. Epub 2026 Apr 24. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
257732pRSFDuet_His-SUMO-NpuNExpression of NpuN, the acetyltransferase protein, for in vitro reaction
257733pRSFduet_His-NpuMExpression of NpuM, the lanthionine synthase, and for co-expression with the precursor peptide and NpuA mutants
257735pETDuet-His-SUMO-NpuA-NpuMFor expression to understand PTM and characterized
257736pETDuet-His-SUMO-TEV-NpuAK1AFor expression and co-expression with the modifying enzyme in the pathway, NpuN (acetyltransferase)
257737pETDuet-His-SUMO-TEV-NpuAK3AFor expression and co-expression with the modifying enzyme in the pathway, NpuN (acetyltransferase)
257738pETDuet-His-SUMO-TEV-NpuAK1AK3AFor expression and co-expression with the modifying enzyme in the pathway, NpuN (acetyltransferase)
257739pETDuet-His-SUMO-NpuAS4A-NpuMFor expression to understand where dehydrations occurred
257740pETDuet-His-SUMO-NpuAC14AFor expression and co-expression with the modifying enzyme in the pathway, NpuM
257741pETDuet-His-SUMO-NpuAC20AFor expression and co-expression with the modifying enzyme in the pathway, NpuM
257742pETDuet-His-SUMO-NpuAC25AFor expression and co-expression with the modifying enzyme in the pathway, NpuM

Antibodies from Article