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Restoring intracellular homeostasis disrupted by synthetic nanoassemblies.

Xing J, Zheng X, Ren Y, Schuler M, Ng DYW, Weil T, Wegner SV, Synatschke CV
Nat Chem Biol. 2026 Oct;22(10):1676-1684. doi: 10.1038/s41589-026-02279-x. Epub 2026 Jul 17. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
257812oxyR-luxA H2O2-responsive bioluminescent reporter plasmid containing the luxCDABE gene cluster.
257813oxyR-msrAMethionine sulfoxide reductases A (MsrA) are expressed in response to H2O2 to selectively reduce the S-epimer of methionine sulfoxide.
257814oxyR-msrBMethionine sulfoxide reductases B (MsrB) are expressed in response to H2O2 to selectively reduce the R-epimer of methionine sulfoxide.
257815pET28a-msrBIPTG-inducible expression of methionine sulfoxide reductase B (MsrB) for the selective reduction of the R-epimer of methionine sulfoxide

Antibodies from Article