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Butyrate causes loss of specific acetylation by the histone acetyltransferase p300.

Jiang M, Psoma A, Lyu J, Chiariello MG, Modderman R, Bianchi F, Incarnato D, Marrink SJ, Jonkers IH, van den Bogaart G
iScience. 2026 Jul 8;29(7):116528. doi: 10.1016/j.isci.2026.116528. eCollection 2026 Jul 17. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
258517p300_N1196D_R1234E_GFPExpression of EGFP fused to core p300 histone acetyltransferase with N1196D + R1234E

Antibodies from Article