RNA-triggered cell killing with CRISPR-Cas12a2.
Scholz P, Thompson J, Crosby KT, Fauth T, Krah NM, Schlauderaff G, Back R, Berkheimer ZA, Jolley A, Sombroek D, Medert R, Zurek C, Dmytrenko O, Wilson E, Schut FT, Rutter J, Zhang X, Krohn M, Jackson RN, Beisel CL, Liu Y
Nature. 2026 May 6. doi: 10.1038/s41586-026-10466-y.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 258653 | pLenti-Cas12a2-EGFP | Expresses mammalian codon-optimized CRISPR-Cas12a2 nuclease (Sulfuricurvum sp. PC08-66) and EGFP under EFS promoter. 3rd-generation lentiviral backbone. |