HLA-E single-chain trimer shields gene-edited allogeneic CAR T cells from NK cell attack.
Apodaca KM, Xu C, Stanton KL, Baroja ML, Alfaro Doblado AR, Engel NW, Wellhausen N, Cox A, Berjis A, Ji M, Bushara O, Perez DM, Welch C, Banerjee E, Assenmacher CA, Sheppard NC, Scholler J, June CH, Carreno BM, Linette GP
Blood Adv. 2026 Jun 23;10(12):4266-4280. doi: 10.1182/bloodadvances.2025016927.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 259551 | pTRPE-HLA-SP-1C-β2m-HLA-E∗01:03 | HLA-E ScT carrying HLA-C signal peptide |