Redirection of SARS-CoV-2 to phagocytes by intranasal sACE2-Fc as a universal decoy confers complete prophylactic protection.
Wang J, Li J, Chin AWH, Luo B, Wei J, Qiu J, Ren J, Xia Y, Braun T, Poon LLM, Feng B
Elife. 2026 May 18;14:RP108883. doi: 10.7554/eLife.108883.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 260562 | AAV-nEF-WT-sACE2-IgG1-Fc | For packaging AAV virus overexpressing WT sACE2-IgG1 Fc |
| 260563 | AAV-nEF-B5-D3-sACE2-IgG1-Fc | For packaging AAV virus overexpressing B5-D3-sACE2-IgG1-Fc |
| 260564 | AAV-nEF-B5-D4-sACE2-IgG1-Fc | For packaging AAV virus overexpressing B5-D4-sACE2-IgG1-Fc |
| 260565 | AAV-nEF-B5-D5-sACE2-IgG1-Fc | For packaging AAV virus overexpressing B5-D5-sACE2-IgG1-Fc |
| 260566 | HDM-CMV-WT-sACE2-IgG1-Fc | Mammalian expression plasmid for WT-sACE2-IgG1-Fc |
| 260567 | HDM-CMV-B5-D3-sACE2-IgG1-Fc-his | Mammalian expression plasmid for B5-D3-sACE2-IgG1-Fc-his |
| 260568 | HDM-CMV-B5-D3-sACE2-IgG1-Fc-LALA-his | Mammalian expression plasmid for B5-D3-sACE2-IgG1-Fc-LALA-his |
| 260569 | HDM-SARS2-Spike-delta21-HA | For packaing SARS-CoV-2 spike pseudotyped lentivirus with HA tag in the spike |
| 260570 | HDM-SARS2-Spike-delta21-D614G | For packaging SARS-CoV-2 D614G spike pseudotyped lentivirus |
| 260571 | HDM-SARS2-Spike-delta21-Alpha | For packaging SARS-CoV-2 Alpha spike pseudotyped lentivirus |
| 260572 | HDM-SARS2-Spike-delta21-Beta | For packaging SARS-CoV-2 Beta spike pseudotyped lentivirus |
| 260573 | HDM-SARS2-Spike-delta21-Gamma | For packaging SARS-CoV-2 Gamma spike pseudotyped lentivirus |
| 260574 | HDM-SARS2-Spike-delta21-Delta | For packaging SARS-CoV-2 Gamma spike pseudotyped lentivirus |
| 260575 | HDM-SARS2-Spike-delta21-Lambda | For packaging SARS-CoV-2 Lambda spike pseudotyped lentivirus |
| 260576 | HDM-SARS2-Spike-delta21-Mu | For packaging SARS-CoV-2 Mu spike pseudotyped lentivirus |
| 260577 | HDM-SARS2-Spike-delta21-Omicron-BA.1 | For packaging SARS-CoV-2 Omicron BA.1 spike pseudotyped lentivirus |
| 260578 | HDM-SARS2-Spike-delta21-Omicron-BA.2 | For packaging SARS-CoV-2 Omicron BA.2 spike pseudotyped lentivirus |
| 260579 | HDM-SARS2-Spike-delta21-Omicron-BA.5 | For packaging SARS-CoV-2 Omicron BA.5 spike pseudotyped lentivirus |